منابع مشابه
Gastric Cancer MicroRNAs Meta-signature
Gastric cancer (GC) is one of the most common types of cancer and the second leading cause of cancer-associated mortality. Identification of novel biomarkers is critical to prolonging patient survival. MicroRNAs (miRNAs) proved to play diverse roles in the physiological and pathological state in cancers including GC. Herein we were aimed at performing a meta-analysis on miRNA profiling studies ...
متن کاملThe Impression of Histone Modification and DNA Methylation in Gastric Cancer Development: Molecular Mechanism Approach
The epigenetic alterations like histone modifications , DNA methylation and others remarkable categories including nucleosome remodeling and RNA mediated targeting have been strongly investigated recently .In this way , beside the notable importance of DNA methylation ,the histone modifications are the most important issues in the tumorogenesis and cancer progression. Moreover...
متن کاملGastric cancer biomarkers; A systems biology approach
Gastric cancer is one of the most fatal cancers in the world. Many efforts in recent years have attempted to find effective proteins in gastric cancer. By using a comprehensive list of proteins involved in gastric cancer, scientists were able to retrieve interaction information. The study of protein-protein interaction networks through systems biology based analysis provides appropriate strateg...
متن کاملMultidisciplinary approach to esophageal and gastric cancer.
Despite marked advances in surgical therapy for patients with esophageal, esophagogastric, and gastric cancers, the overall prognosis of these patients has not markedly improved during the past decades. Multidisciplinary approaches using adjuvant postoperative and neoadjuvant preoperative therapeutic principles have received increasing attention with regard to the management of these patients. ...
متن کاملMolecular Signaling in Tumorigenesis of Gastric Cancer
Gastric cancer (GC) is regarded as the fifth most common cancer and the third cause of cancer-related deaths worldwide. Mechanism of GC pathogenesis is still unclear and relies on multiple factors, including environmental and genetic characteristics. One of the most important environmental factors of GC occurrence is infection with Helicobacter pylori that is classified as class one carcinogens...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2019
ISSN: 0923-7534
DOI: 10.1093/annonc/mdz155.142